White Matter Hyperintensity (WMH) detection

Discover SPIN WMH

efficient and accurate quantification and monitoring of white matter lesion 
easy to use, robust quantification tool
objective and fast interpretation of the MRI data
better evaluation of white matter lesions over the course of the disease and its treatment

How does SPIN WMH work

Most current WMH semi-automated approaches require multiple MR data sets. This requires more time clinically. We propose to use only a 3D FLAIR to determine lesion, brain, and ventricle volumes automatically and to label the lesion type. We proposed a high spatial frequency suppression method only using 3D FLAIR images. This has been implemented and incorporated into SPIN. In order to achieve more accurate segmentation results, we also implemented several functions in the post-processing to assist manual segmentation. They include: “mask modifies (MODI)”, “contour drawing (PEN)” and “click pick up (PICK)”. We are currently testing this on a series of 138 MS patients to compare it to a manual approach. No manufacturer yet offers automated WMH segmentation and even our manual segmentation would compete their functions.  

Clinical use:

  • Multiple Sclerosis
  • Dementia
  • Parkinson's disease 
  • Stroke
The SPIN-Research software download link can be found below, at our spinoff company, SpinTech, Inc.  Thank you.
Spin software

Magnetic Resonance Innovations, Inc. 
30200 Telegraph Road Ste. 104
Bingham Farms, MI 48025
United States of America


Email: [email protected]
Fax: +1 (313) 758 0068
Tel: +1 (313) 758 0065
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