PWI (Perfusion Weighted Imaging)

Discover SPIN PWI

​​​​New algorithms for estimating perfusion to brain tissue.

How does PWI work?

PWI is a well established MRI method for studying cerebral hemodynamics and has found various applications in tumor, angiogenesis and stroke imaging. The hemodynamic characteristics are determined by creating maps of various parameters, such as: cerebral blood flow (CBF), cerebral blood volume (CBV), mean transit time (MTT) and time to bolus peak (TTP), and these parameter maps are derived from the evolution of the intensity of T2*-weighted gradient- or spin-echo, echo-planar images as a gadolinium contrast agent bolus passes through the blood vessels.
Through the use of these maps, it is possible to visualize the passage of blood throughout the brain and to identify any regions of abnormal behavior. Quantification of these hemodynamic parameters is possible, utilizing the central volume theorem and a subsequent deconvolution technique. Further, our module is compatible with data from a double injection procedure, allowing more accurate estimation of the arterial input function.

Clinical use:

  • Alzheimer’s disease
  • Multiple sclerosis
  • Stroke
  • Traumatic Brain Injury

The SPIN-Research software download link can be found below, at our spinoff company, SpinTech, Inc.  Thank you.
Spin software

Magnetic Resonance Innovations, Inc. 
30200 Telegraph Road Ste. 104
Bingham Farms, MI 48025
United States of America


Email: [email protected]
Fax: +1 (313) 758 0068
Tel: +1 (313) 758 0065
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